search slide
search slide
pages bottom
About Me

Actos and Bladder Cancer: A Case of Cause and Effect

Type 2 diabetes, which is also called adult-onset diabetes and non-insulin-dependent diabetes, is a serious illness suffered by many individuals around the globe. This persistent disease influences the body’s behavior in processing sugar/glucose, which is the body’s main source of energy. There are ways to prevent this type of diabetes; however, if unchecked and allowed to develop, it would result to lifetime suffering.

Though anyone can be susceptible to Type 2 diabetes, those who are 45 years old or above and most often inactive, have low HDL cholesterol or a high triglycerides level, hypertensive, overweight and have been diagnosed with pre-diabetes or gestational diabetes, are more prone to developing it.

A person will start suffering from the dreaded diabetes when he/she begins to have high blood sugar. This happens when his/her pancreas (the gland near our stomach which secretes the hormone insulin and controls the amount of sugar in the bloodstream) stops to produce, or begins to produce, very little insulin or when it no longer responds to insulin. This sugar or glucose comes from all the food and beverages a person consumes; it is also the cell’s source of energy – the energy the body needs to be able to perform daily activities normally.

In 1999 the oral diabetes medicine Actos (also called Pioglitazone), from Takeda Pharmaceuticals, was approved by the US Food and Drug Administration for market release. The drug was intended to help Type 2 diabetics control their blood sugar level by increasing their sensitivity to insulin. Actos also helped decrease the amount of glucose that the liver releases and it was claimed safe even if taken without food.

It should be noted, though, that Actos is not a cure to Type 2 diabetes, to which there is no known cure; it only helps the body to manage glucose level and absorption of insulin. In 2008 Actos became the 10th most prescribed drug in the US. Its efficacy was, likewise, recognized in a number of European countries, like France and Germany.

Studies that showed Actos’ effect in increasing the risk of bladder cancer surfaced in 2010, though, and despite the fact that an earlier study, conducted in 2005, already arrived at this same conclusion, this finding was never brought to the attention of the FDA. Cases of adverse effects and deaths due to Actos piled one on top of another. Despite this, Takeda kept denying that Actos increased the risk in the development of bladder cancer. Besides bladder cancer, the drug was also found to cause severe, permanent damage to vital internal organs.

As early as 2011 at least 10,000 lawsuits were filed against Actos’ manufacturer Takeda. The company’s continuous denial of the adverse effects of Actos, despite knowledge of it and the obvious evidences render it much more liable as it openly violated patients’ trust.

Symptoms of bladder cancer include: presence of blood in urine, constant urgency and straining to empty bladder, frequent urination and feeling of pain when urinating.

Grout Cleaning Tips

Grout is the substance used to fill the spaces between floor and wall tiles. A mixture of water, cement, sand, and color tint, it is a fairly porous substance that, over time, can fill with dirt, mold, and other unpleasant contaminants. Proper grout sealing can help to prevent these problems from occurring, but even the best sealing job may not be enough to prevent grout stains from appearing over time. Fortunately, cleaning your grout, while sometimes tedious, is fairly easy work.

Grout cleaning should begin with the cleaning solution itself. In most cases, grout can effectively be cleaned with do-it-yourself cleaning solutions, such as a mixture of equal parts baking soda, salt, and water. Spread this cleaning solution over any dirty areas and allow to soak for a few minutes. Then, with a stiff brush, scrub the area clean. You may also want to consider applying a bleach solution if there is any mildew or mold in your grout, as bleach will kill the spores and prevent them from growing further.

Once these tasks are complete, you can either wipe the area down with a wet towel or, even better, use a wet/dry vacuum to pull up any remaining dirt particles from the grout, leaving it looking clean and new. After this is done, you might want to consider applying a sealant to help prevent dirt from collecting in the future.

Common Causes of Burn Injuries

Burn injuries are particularly damaging in a way that many other types of injuries are not. Burns can occur extremely quickly, and if left untreated, can result in serious infections or even death. Therefore, it is important to understand what the possible causes of burn injuries can be, and how they can be avoided.

The most common cause of burn injuries is exposure to fire. Explosions, natural disasters, or even simply routine accidents can all expose an individual to serious burn injuries. Car accidents can similarly place an individual at risk of fire burn injuries.

Boiling liquids and steam can also cause serious burn injuries. In fact, except for extremely minor cases, these types of burn injuries are often more severe, as boiling liquids can more easily pass through several layers of tissue before the source of damage is stopped.

Chemical burns are another serious form of burn injury that can have serious long-term consequences. Depending on the type of chemical involved and the method of exposure, chemical burns can be among the most severe that an individual can suffer. Furthermore, because of the possibility of inhalation, exposure to hazardous chemicals which can result in burn injuries may even be life-threatening.

National Dog Bite Prevention Week

This week is National Dog Bite Prevention Week.

preventing dog bitesKeeping their pets from biting innocent people should always be a dog owner’s priority, but sadly this is not always the case. More than 4.5 million people in the United States suffer dog bites every year. Most of these victims are young children and many of the incidents are completely preventable.

Postal workers are also in danger of sustaining dog bite injuries. In 2012, almost six thousand postal workers were attacked by dogs while trying to deliver the mail.

When dogs bite innocent people, their owners are the ones who can be held liable for the injuries that occur. To prevent being bitten by a dog, do not make any moves it may perceive as threatening, don’t put your hands near its mouth, and always respect their personal space. Being aware of how the dog feels can allow you to avoid a painful and injurious dog bite.

 

New Hampshire School District Sued by Fallen Girl’s Family

The School District in Salem, New Hampshire is facing a lawsuit as a result of a fall sustained by a student at a track and field event three years ago.

The then 12-year-old girl was taking a seat in the bleachers when she fell through a gap that was as wide as 15 inches and sustained serious injuries that included broken bones and forced her to be confined to a wheelchair for eight weeks.

The suit is being filed now rather than years ago in anticipation of any potential long-term effects that would not have been apparent at the time.

The school district has since made measures to prevent such falls from occurring again, but the lawsuit contends that they do not go far enough. The lawsuit also names the city of Salem as a defendant, but the city believes it has no liability and should not be included in the proceedings.

« Previous Entries Next Entries »